Retinoic acid induces changes in electrical properties of adult neurons in a dose- and isomer-dependent manner

Retinoic acid induces changes in electrical properties of adult neurons in a dose- and isomer-dependent manner.

The electrical activity of neurons is known to play a role in neuronal development, as well as repair of adult nervous tissue. For example, the extension of neurites and motility of growth cones can be modulated by changes in the electrical firing of neurons. The vitamin A metabolite retinoic acid also plays a critical role during nervous system development and is also known to elicit regenerat...

Retinoic acid induces changes in electrical properties of adult neurons, in a dose-

8 9 Abbreviated title: Retinoic-acid induced changes in neuronal firing 10 Corresponding Author: 11 G.E. Spencer, 12 Dept. Biological Sciences, 13 Brock University, 14 St. Catharines, 15 ON. Canada. L2S 3A1 16 Tel: 905 688 5550 ext 3391 17 Email: [email protected] 18 19

Retinoic acid receptor-dependent survival of olfactory sensory neurons in postnatal and adult mice.

To address the hypothesis that retinoids produced by synthesizing enzymes present in the primary olfactory system influence the mouse olfactory sensory map, we expressed a dominant-negative retinoic acid receptor selectively in olfactory sensory neurons. We show that neurons deficient in nuclear retinoid signaling are responsive to odors and form correct odorant receptor-specific axonal project...

Umbelliprenin, a bioactive constituent from the genus Ferula has cytotoxic and apoptotic activity in a dose- and time-dependent manner

a contrastive analysis of concord and head parameter in english and azerbaijani

این پایان نامه به بررسی و مقایسه دو موضوع مطابقه میان فعل و فاعل (از نظر شخص و مشار) و هسته عبارت در دو زبان انگلیسی و آذربایجانی می پردازد. اول رابطه دستوری مطابقه مورد بررسی قرار می گیرد. مطابقه به این معناست که فعل مفرد به همراه فاعل مفرد و فعل جمع به همراه فاعل جمع می آید. در انگلیسی تمام افعال، بجز فعل بودن (to be) از نظر شمار با فاعلشان فقط در سوم شخص مفرد و در زمان حال مطابقت نشان میدهند...